Scs2p
WebbDOI: 10.1016/J.BBRC.2007.10.079 Corpus ID: 22143921; The yeast VAP homolog Scs2p has a phosphoinositide-binding ability that is correlated with its activity. … Webb10 nov. 2024 · Abstract. In the yeast Saccharomyces cerevisiae, the Opi1p repressor controls the expression of INO1via the Opi1p/Ino2p-Ino4p regulatory circuit. Inositol …
Scs2p
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WebbThe yeast VAMP-associated protein (VAP) homolog Scs2p is an endoplasmic reticulum (ER)/nuclear membrane protein that binds to an FFAT (diphenylalanine in an acidic tract) … Webb22 sep. 2024 · A prominent ~50-kDa sumoylated protein accumulates in a Ulp1 coiled-coil domain mutant; that was identified as Scs2, an endoplasmic reticulum (ER) membrane protein that regulates phosphatidylinositol synthesis and lipid trafficking. show that the Yet1p-Yet3p complex acts in derepression of INO1 through physical association with …
Webbffat 모티브(ffat는 산성로[nb 1] 내의 2개의 페닐알라닌(ff)의 약어)는 6개의 정의된 아미노산과 vap 단백질 패밀리의 단백질에 결합하는 인접 잔류물의 단백질 배열 … WebbA common way in which they target contacts is by binding to the ER proteins, VAP/Scs2p, while the second membrane is targeted by other interactions with lipids or proteins. We have studied the cross-talk of secretory SNARE proteins and their regulators with ORP/Oshp and VAPA/Scs2p at ER-plasma membrane contact sites in yeast and murine …
Webb11 juni 2004 · Scs2p is required for normal localization of Opi1p , and deletion of SCS2 represses INO1, causing a mild inositol auxotrophy . Here, we found a molecular … Webb6 mars 2024 · 4 Scs2p BiFC interactions with itself, the ER SNARE Sec22p and the plasma membrane SNARE Sso1p are disturbed in the SNARE mutant strain in vivoAdditionally, the Sec22p-Sso1p BiFC interaction is usually misplaced. = 1, lysed, and subjected to anti-HA immunoprecipitations.
WebbThe Saccharomyces cerevisiae suppressor of choline sensitivity ( SCS2) gene is a multicopy Suppressor of mec1 telomeric silencing defects [3]. We identified SCS2 (suppressor of choline sensitivity), a gene previously isolated as a suppressor of defects in inositol synthesis [3]. Deletion of SCS2 resulted in decreased telomeric silencing, and ...
Webb10 nov. 2024 · In the yeast Saccharomyces cerevisiae, the Opi1p repressor controls the expression of INO1 via the Opi1p/Ino2p-Ino4p regulatory circuit. Inositol depletion favors Opi1p interaction with both Scs2p and phosphatidic acid at the endoplasmic reticulum (ER) membrane. Inositol supplementation, however, favors the translocation of Opi1p from … terpin mekongWebb3 mars 2011 · Scs2p belongs to a conserved family of ER-localized VAPs, which interact with a variety of intracellular proteins often through binding to a FFAT motif as found in Opi1p (Lev et al., 2008). Many FFAT motif–containing proteins, including oxysterol binding proteins and ceramide transport proteins, ... terpinya ukraineWebb10 nov. 2024 · A strain devoid of Scs2p (scs2Δ) and a mutant, OPI1FFAT, lacking the ability to interact with Scs2p were utilized to examine the specific role(s) of the Opi1p–Scs2p … terpin hidratWebb11 dec. 2024 · In this scenario, it can be expected that Sec9p (SNAP25) is recruited by an Osh-Scs2p complex, which might then induce tethering between ER and PM. As no … terpinyl butyrateWebb14 jan. 2011 · However, most of Scs2p(P44,51S) and Scs2p(P51,58S) were found in the pellet following centrifugation, indicating that these mutant Scs2 proteins formed an … terpinz dispensaryWebbScs2p was subsequently identified as an integral mem-brane protein of the ER (17) and homolog of the mammalian VAMP (32). The scs2 mutant exhibits a relatively weak Ino phenotype at 30 °C, which becomes stronger (more visible in platetests)atgrowthtemperaturesof34 °Corhigher(Fig.2,A terpisah bahasa inggrisWebbInteraction between repressor Opi1p and ER membrane protein Scs2p facilitates transit of phosphatidic acid from the ER to mitochondria and is essential for INO1 gene expression … terpisah