WebIn this study, we made use of a Nestin-CreERT2/R26R-YFP transgenic mouse model in which the CreERT2 activates the expression of YFP in multipotent neural stem cells upon tamoxifen application. Humoral factors, such as the levels of estrogens, have been reported to affect the hippocampal neurogenesis. WebA Biblioteca Virtual em Saúde é uma colecao de fontes de informacao científica e técnica em saúde organizada e armazenada em formato eletrônico nos países da Região Latino-Americana e do Caribe, acessíveis de forma universal na Internet de modo compatível com as bases internacionais.

Antonio Tomasso - Research Fellow - LinkedIn

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中科院深圳先进院彭勃团队成功破解脑内再殖小胶质细胞起源之谜

WebWe used Nestin CreERT2 mice to trace SC-NSCs descendants in the spinal cord of mice subjected to SCI. While mice carrying the suicide gene thymidine kinase (TK) along with the GFP reporter, under the control of the Nestin promoter regions (NestinTK mice) were used to label and selectively kill SC-NSCs. WebNov 25, 2008 · Nestin-CreER T2 /R26R-YFP mice were crossed with floxed Cdk5 (fCdk5) mice (18, 19) to generate Cdk5 nKO mice (Fig. 2A). In these mice, the nestin promotor drives the expression of the Cre recombinase-modified estrogen receptor (CreER T2) fusion protein in SGZ progenitors. ... nestin-CreERT2; viral-mediated gene transfer; WebTo examine rNSC behavior and neurogenesis in SGZ in vivo, we identified newborn cells via 5-ethynyl-20-deoxyuridine (EdU) (a thymidine analog) labeling of dividing rNSCs (a combined result of proliferation, survival, and differentiation) in Nestin-GFP transgenic mice over 7 days (once per day) or 30 days (once every 4 days) and carried out … buck tooth dinosaur