Chrysophanol是什么
Chrysophanol, also known as chrysophanic acid, is a fungal isolate and a natural anthraquinone. It is a C-3 methyl substituted chrysazin of the trihydroxyanthraquinone family. Chrysophanol (other names; 1,8-dihydroxy-3-methyl-anthraquinone and chrysophanic acid) was found commonly … See more Chrysophanol was first noted from Rheum rhabarbarum which is a plant belonging to the Polygonaceae family. It has since been discovered to be present in various families such as Liliaceae, Meliaceae, Asphodelaceae … See more Chrysophanol can act as an antineoplastic drug. This has been shown in multiple organisms. It has been reported that chrysophanol causes necrosis-like cell death in renal … See more Chrysophanol has been shown to be able to be co-administered with atorvastatin, to lower cholesterol levels. This is due to the different … See more Chrysophanol has been shown to exhibit a variety of effects. It was shown in 2015 to lower cholesterol and triglyceride levels in zebrafish, as well as increase the frequency of … See more Chrysophanol can alleviate diabetic nephropathy by inactivating TGF-β/EMT signalling. It also has the potential to protect bronchial cells from cigarette smoke extract by … See more Chrysophanol is naturally made by a variety of plant species. The most intake is from consumption of rhubarb. See more Anthraquinones, chrysophanol derivatives among them, have been shown to be hepatotoxic. They can cause apoptosis in normal human liver cells. Chrysophanol derivatives such as … See more WebIn Meyler's Side Effects of Drugs (Sixteenth Edition), 2016. Tumorigenicity. Several anthranoid derivatives (notably the aglycones aloe-emodin, chrysophanol, emodin, and physicon) are genotoxic in bacterial and/or mammalian test systems [3], and two anthranoid compounds (the synthetic laxative dantron and the naturally occurring l …
Chrysophanol是什么
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WebDec 1, 2024 · Chrysophanol, physcion, aloe-emodin and emodin were confirmed by GC–MS and the possible main cleavage pathways of fragment ions are discussed in this study. Rhubarb is a traditional Chinese medicinal herb which required an effective evaluation method to quantitate the four major active anthraquinone compounds described. The … WebChrysophanol is a well-known intermediate toward biosynthesis of xanthone type of compounds such as secalonic acids. 175 If looking at the structure of chrysophanol …
WebMay 26, 2024 · Chrysophanol regulates ROS production and the expression of p53, p21, cyclinD1, CDK4, cdc2, CDK2, and cell cycle progression. (a) The level of intracellular ROS determined by using the CellROX® oxidative stress reagents in chrysophanol-treated cells (30 and 70 μm) or control (Ctrl, 0 μm), and the fluorescence detected by flow … WebChrysophanic acid. Molecular Formula CHO. Average mass 254.238 Da. Monoisotopic mass 254.057907 Da. ChemSpider ID 9793.
WebChrysosplenol D C18H16O8 CID 5280699 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities ... WebChrysophanol (Chr) is one of the most important anthraquinone components isolated from plants of the Rheum genus. Current reports show that in Rheum officinale, Chr is …
WebMar 14, 2024 · of chrysophanol in combination with other drugs can reduce toxicity and enhance efficacy. Summary Chrysophanol can be used in many diseases. Future research direc-tions include how the concentration of chrysophanol affects pharmacological effects and toxicity; the mechanism of synergy between chrysophanol …
WebObjective: Chrysophanol is a natural anthraquinone, also known as chrysophanic acid and 1,8-dihydroxy-3-methyl-anthraquinone. It has been widely used in the food and … floward contact numberWebDec 15, 2024 · Objective: Chronic obstructive pulmonary disease (COPD) is a common respiratory disease characterized by the persistent airflow obstruction. Chrysophanol, … floward contactgreek country houseWebChrysophanol C15H10O4 CID 10208 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more. … greek counterpart of plutoWebJul 20, 2024 · A simple and sensitive liquid chromatography-tandem mass spectrometric bioanalytical method for the simultaneous determination of both anthraquinone glycosides and their aglycones, including emodin, emodin-8-O-β-d-glucoside, chrysophanol, chrysophanol-8-O-β-d-glucoside, physcion, and physcion-8-O-β-d-glucoside , in a low … floward holding ltdWebChrysophanol analytical standard; CAS Number: 481-74-3; EC Number: 207-572-2; Synonyms: 1,8-Dihydroxy-3-methylanthraquinone,3-Methylchrysazin,Chrysophanic acid; find Supelco-01542 MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich greek country musicWebOct 31, 2024 · Anthraquinones (AQs) are present in foods, dietary supplements, pharmaceuticals, and traditional treatments and have a wide spectrum of pharmacological activities. In the search for anti-cancer drugs, AQ derivatives are an important class. In this study, anthraquinone aglycons chrysophanol (Chr), emodin (EM) and FDA-approved … greek countries